Raws li kev ua liaj ua teb ntsib kev kub ntxhov los tsim ntau dua nrog cov khoom siv tsawg dua, kev tsim kho tshiab hauv kev tiv thaiv qoob loo lom neeg tau txav mus rau qhov tsis tau muaj dua. Micropep Technologies yog nyob rau hauv pem hauv ntej ntawm qhov kev hloov pauv no nrog nws AI -lub zog nrhiav pom platform, Krisalix, tsim los txhawm rau txhim kho micropeptide-raws li biosolutions. Hauv kev sib tham tsis ntev los no nrog AgriBusiness Ntiaj teb no, Mikael Courbot, Tus Thawj Saib Xyuas Kev Lag Luam ntawm Micropep Technologies, tau qhia tias AI tab tom hloov kho qhov kev tshawb pom, nthuav tawm lub peev xwm ntawm peptide tsim, thiab rov txheeb xyuas seb yuav ua li cas tshiab, kev ua haujlwm ruaj khov ntawm kev ua lag luam.
Reshaping Crop Protection Discovery Los ntawm AI
Artificial txawj ntse yog qhib qhov muaj peev xwm tshiab rau kev ceev thiab qhov tseeb ntawm kev tshawb pom hauv kev tiv thaiv qoob loo. Courbot piav qhia tias cov platforms zoo li Krisalix tau hloov pauv tag nrho cov txheej txheem kev txhim kho los ntawm kev sib koom ua ke tsim thiab kwv yees AI nrog biology, chemistry, thiab kev tsim khoom rau hauv kev sib koom ua ke.
"Krisalix ua kom muaj kev hloov pauv los ntawm cov qauv tsim qauv mus rau kev kuaj sim hauv lub lis piam xwb tsis yog lub hlis," nws hais. "Qhov ntawd txhais tau hais tias peb tuaj yeem ua kom ncua sij hawm tshawb pom rau cov qauv tshiab ntawm kev ua haujlwm ntawm fungicides, tshuaj tua kab mob, thiab tshuaj tua kab."
Tsis zoo li dav dav -Lub hom phiaj AI cov cuab yeej tsom mus rau genomics lossis duab, Krisalix yog lub hom phiaj- tsim rau peptide-raws li biosolutions. Nws optimizes molecule kev ua tau zoo thaum tseem kwv yees manufacturability thiab stability, muaj peev xwm hloov pauv li cas biocontrols nrhiav tau thiab coj mus rau kev lag luam.
Courbot hais ntxiv tias "Qhov no sawv cev ntau dua li kev nrawm dua digital xwb," "Nws cim qhov kev tsim kho tshiab ntawm yuav ua li cas yav tom ntej biocontrols raug tsim."
Nthuav Peptide Design Beyond Fungicides
Micropep thawj biofungicide, MPD-01, yog lub tuam txhab thawj qhov kev lees paub loj ntawm Krisalix platform, tab sis nws tsuas yog qhov pib. Courbot xav txog yav tom ntej dav dav rau peptide tsim.
"Nrog Krisalix lub peev xwm ua qauv, peb tuaj yeem txuas ntxiv peptide tsim kom deb tshaj li cov tshuaj fungicides thiab tshuaj tua kab mob peptide technology," nws piav qhia. "Peb tab tom saib rau hauv bioherbicides, biopesticides, thiab txawm tias cov nroj tsuag resilience thiab khoom noj khoom haus."
Krisalix lub tshuab tshuaj ntsuam xyuas virtual tuaj yeem ua qauv rau ntau lab tus neeg sib tw peptide thiab qeb duas qhov kev cia siab tshaj plaws raws li kev sib khi zoo, kev ua tau zoo, thiab kev ruaj ntseg. "Txhua yam peb xav tau yog lub hom phiaj protein," Courbot hais. "Lub platform tuaj yeem ua tus so ntawm cov khoom siv lead ua."
Vim hais tias peptides tshwm sim nyob rau hauv tag nrho cov nroj tsuag thiab kab mob, tib lub moj khaum yuav siv tau rau ntau yam kev ua liaj ua teb cov nyom, los ntawm biotic kev nyuaj siab los ntawm kab tsuag thiab kab mob mus rau abiotic kev nyuaj siab xws li tshav kub los yog drought. Sij hawm dhau mus, Courbot cia siab tias Krisalix yuav dhau los ua lub hauv paus tsim lub cav rau kev ruaj ntseg micropeptide-raws li cov khoom siv qoob loo uas muaj kev nyab xeeb dua, txhim kho sai dua, thiab hloov tau yooj yim hla cov qoob loo thiab huab cua.
Tshawb nrhiav Cov Qauv Tshiab ntawm Kev Ua Haujlwm
Ib qho ntawm Krisalix lub zog loj tshaj plaws nyob rau hauv nws lub peev xwm txav mus dhau qhov kev paub ntawm kev ua thiab kwv yees tag nrho cov kev sib cuam tshuam biochemical tshiab ntawm peptides thiab lawv cov hom phiaj protein. Los ntawm kev sib txuas lub xeev- ntawm-- kev kwv yees cov qauv ntawm cov protein nrog AI-raws li peptide binder tiam, lub platform tuaj yeem sim ua li cas peptides cuam tshuam nrog cov protein tshwj xeeb los thaiv lossis hloov kho lawv txoj haujlwm.
"Qhov no tso cai rau peb txheeb xyuas micropeptides hauv ntau lub thev naus laus zis," Courbot tau hais. "Qhov ntawd suav nrog cov tshuaj tua kab mob peptides uas cuam tshuam cov kab mob fungal, peptide-protein interaction blockers, thiab micropeptides uas hloov pauv cov noob txhais lus."
Txoj hauv kev zoo no yog qhov tseem ceeb rau kev tawm tsam kev tawm tsam thiab nthuav dav kev ua haujlwm lom neeg thaj av. "Los ntawm kev tshawb nrhiav cov qauv tshiab ntawm kev nqis tes ua," nws hais tias, "peb tuaj yeem pab ua kom ntseeg tau tias kev tiv thaiv qoob loo lom neeg txuas ntxiv mus ntxiv nrog rau kev hloov pauv kev ua liaj ua teb."
Streamlining Cov ntaub ntawv rau npe
AI tsis yog tsuas yog ua kom nrhiav tau sai xwb: nws kuj tseem txhim kho qhov nruj thiab traceability ntawm cov ntaub ntawv tom qab nws. Courbot sau tseg tias Krisalix txhim kho kev tsim tawm thiab pob tshab hauv peptide R & D los ntawm cov ntaub ntawv hauv nruab nrab thiab MLOps cov kav dej uas muaj zog uas tsim cov txheej txheem, cov ntaub ntawv rov qab tau.
Los ntawm kev koom ua ke nrog ADOPT Knowledge Engine, tag nrho cov ntaub ntawv kev sim yog lub hauv paus los xyuas kom muaj kev rov tsim dua tshiab thiab txhawb kev tsim cov ntaub ntawv zoo tshaj - cov ntaub ntawv zoo rau kev tswj xyuas. Courbot hais tias "Vim tias cov txheej txheem tswj hwm kev noj qab haus huv tseem tab tom hloov zuj zus, muaj cov ntaub ntawv - cov txheej txheem tsav yog qhov tseem ceeb," Courbot hais. "Krisalix tsis tsuas yog tso cai rau kev tsim cov molecules zoo dua tab sis kuj tseem muaj cov ntaub ntawv kev ncaj ncees thiab kev taug qab uas cov tswj hwm xav tau."
Saib tom ntej: AI ua tus Catalyst rau Sustainable Innovation
Rau Courbot, txoj haujlwm ntawm Micropep nyuam qhuav pib. "Micropeptides sawv cev rau chav kawm tshiab ntawm biosolutions uas sib xyaw ua ke ntawm cov tshuaj chemistry nrog kev ruaj ntseg ntawm cov roj ntsha," nws hais. "Kev hloov pauv sai ntawm AI systems zoo li Krisalix tau ua rau cov txheej txheem tshawb pom muaj zog. Peb tab tom kawm tas li thiab txhim kho kev ua tau zoo nrog txhua lub voj voog."
Raws li Micropep txoj kev koom tes nthuav dav nrog cov tuam txhab ua lag luam xws li Corteva thiab FMC, Krisalix tau npaj los txheeb xyuas cov cim tshiab ntawm cov khoom siv qoob loo uas txawv los ntawm kev ua tau zoo, kev nyab xeeb, thiab kev ua kom muaj zog.
"Thaum kawg," Courbot xaus lus, "AI- tsav peptide innovation yuav ua rau kev ua liaj ua teb mus rau yav tom ntej uas muaj txiaj ntsig zoo dua qub, rov ua dua tshiab, thiab ruaj khov."
